Investigating the Biology and Genetic Basis of Stress Adaptation in Cryptococcus neoformans

BJ Chadwick - 2023 - search.proquest.com
yeast and human pathogen Cryptococcus neoformans. Science (… CRZ1/SP1-like gene
links survival under limited aeration, cell integrity and biofilm formation in the pathogenic yeast

The transcription factor Pdr802 regulates titan cell formation and pathogenicity of Cryptococcus neoformans

JCV Reuwsaat, DP Agustinho, H Motta, AL Chang… - Mbio, 2021 - Am Soc Microbiol
… IMPORTANCE The pathogenic yeast Cryptococcus neoformansCRZ1/SP1-like gene
links survival under limited aeration, cell integrity and biofilm formation in the pathogenic yeast

The transcription factor Pdr802 regulates Titan cell formation, quorum sensing, and pathogenicity of Cryptococcus neoformans

JCV Reuwsaat, DP Agustinho, H Motta, H Brown… - bioRxiv, 2020 - biorxiv.org
… IMPORTANCE The pathogenic yeast Cryptococcus neoformansneoformans to survive
and proliferate in the lung, and … cells under conditions that challenge cell or cell wall integrity

[HTML][HTML] Molecular Dissection of Crz1 and Its Dynamic Subcellular Localization in Cryptococcus neoformans

BJ Chadwick, BE Ross, X Lin - Journal of Fungi, 2023 - mdpi.com
… to regulate gene expression. In the fungal pathogen Cryptococcus neoformans, calcineurin–…
calcium homeostasis, thermotolerance, cell wall integrity, and morphogenesis. How Crz1 …

[PDF][PDF] Hyphal morphogenesis of the human fungal pathogen cryptococcus neoformans

J Lin - 2019 - getd.libs.uga.edu
… This molecular and genetic study has advanced our … link between hyphal filamentation
and virulence in C. … Cryptococcus neoformans: pseudohyphal forms surviving culture with …

[HTML][HTML] Zinc Finger Proteins in the Human Fungal Pathogen Cryptococcus neoformans

YH Li, TB Liu - International journal of molecular sciences, 2020 - mdpi.com
… involved in virulence, including cell wall integrity, nitrosative stress, … essential for cell wall
damage repair, biofilm formation, and … of proliferation and survival under reduced aeration [99]. …

[HTML][HTML] Updating insights into the regulatory mechanisms of calcineurin-activated transcription factor Crz1 in pathogenic fungi

Y Yang, P Xie, Y Li, Y Bi, DB Prusky - Journal of Fungi, 2022 - mdpi.com
… Therefore, Crz1 was crucial for the survival of yeast cells underCryptococcus neoformans
Hypoxic adaptation … Other genes involved in maintaining cell wall integrity such as CRH1, …

The Cys2His2 zinc finger protein Zfp1 regulates sexual reproduction and virulence in Cryptococcus neoformans

CL Fan, LT Han, ST Jiang, AN Chang, ZY Zhou… - Fungal genetics and …, 2019 - Elsevier
Cryptococcus neoformans is a ubiquitous yeast pathogen that … Survival data from the murine
experiments were statistically … how the Zfp1 protein regulates cell membrane integrity in C. …

[HTML][HTML] CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1 (Crz1) transcription factor as a promising therapeutic target in echinocandin-resistant …

A Ceballos-Garzon, E Roman, J Pla, F Pagniez… - Plos one, 2022 - journals.plos.org
… in biofilm formation, we compared the ability to form biofilms … Regarding survival strategy,
the fungal cell wall represents … the cell wall integrity (CWI) pathway [60]. The concept that the …

[PDF][PDF] The transcription factor Pdr802 regulates Cryptococcus neoformans Titan cell production and pathogenicity

JCV Reuwsaat, H Motta, DP Agustinho, H Brown… - bioRxiv, 2020 - scholar.archive.org
… is a ubiquitous, opportunistic fungal pathogen that kills … We next assessed the long-term
survival of C57BL/6 mice … to WT cells under conditions that challenge cell or cell wall integrity, …